How Genetics Play a Role in Your Health
When it comes to your health, the answers are in your genes. Now, you have the tool that gives you those answers. Now, you have the nutraMetrix®️ Gene SNP™ DNA Analysis Program.
Your DNA tells a story. With the nutraMetrix®️ Gene SNP™ DNA Analysis, you can gain insight into your genetics and how they impact your health. You may simply want to know what role your genes play in digestive health, how well your body copes with the stress of physical activity; how environmental factors affect your body and uncover how your genetics and lifestyle impact your health.
Gene SNP delivers answers exclusively tailored to you, your body and your lifestyle. You have the tool; use it. No more guesswork; get the facts – nutraMetrix®️ Gene SNP DNA Analysis.
Learn More About Your DNA
How Does It Work?
In the convenience of your health professional's office, a sample is collected from your cheek cells, which contain your DNA. The swabs are put into the provided, specialized collection container after drying. The swabs are sent with the Genetic Assessment Request Form and the Consent Form in the included mailing tube provided in the kit to the processing laboratory. (S&H not included)
Once at the certified laboratory, DNA is extracted from your swabs and then prepared for analysis. The DNA is analyzed using the latest genotyping technology to give the most accurate results. Once all of this data is compiled, it is entered into a sophisticated, algorithm-based computer software program that generates a confidential, easy-to-follow Gene SNP Health Action Plan to be reviewed by the health professional or a qualified staff provider and the patient. Typically, it takes six to ten weeks for your healthcare provider to receive your Gene SNP Analysis results.
In combination with interpretation from your health professional, Gene SNP DNA Analysis provides valuable information about gene expression and its impact on factors like cardiovascular, endocrine and mental/emotional health. In addition, Gene SNP DNA Analysis also looks at select nutrients and fitness factors that may contribute to chronic health concerns including obesity. Dietary intervention, based on knowledge of nutritional requirement, nutritional status, and genotype can be used to prevent, mitigate or remedy chronic disease.
How Genes Affect You
No two people have the same fingerprint. Like our fingerprints, our genetic variations are unique identifiers which make us different from every other person. It's the variations in genes that make us who we are. From our gender; the color of our hair, eyes and skin; the types of foods that work best with our bodies; and even the type of exercise designed to maximize our individual performance, our genes are the instruction manual for the creation and maintenance of our bodies.
Our genes are composed of combinations of protein bases. While there are only four possible bases, they can be combined in billions of ways to code for countless functions in the body. These four bases make up the DNA alphabet and combine to form words and phrases that give instructions to your body for everything from how your cells function to the color of your hair. Sometimes, when cells in the body replicate to make new cells, mistakes are made. By changing just one letter or just one base, the gene now has a totally new meaning and function. These variations are called single nucleotide polymorphisms (or SNPs).
These small variations in DNA are expressed in many ways. They can influence how we metabolize food and what types of exercise are best suited for our bodies. By identifying our own unique gene variations, we can customize lifestyle approaches and nutritional supplementation to maximize our genetic potential promoting optimal health never before achieved.
Gene SNP
OUR TEST:
• Obtains genetic sample through a practitioner administered cheek swab
• Evaluates 48 genes and the multiple areas of health impacted
• Evaluates diet, lifestyle, exercise, sleep and emotional health habits
OUR PLAN: Delivers a comprehensive Health Action Plan with concrete suggestions for achieving your optimal health potential
OUR SUPPLEMENTS: Based on a careful analysis of your genetics, diet and lifestyle, we assist the practitioner to prioritize supplementation based on a patient’s genetic blueprint.
OUR COMMITMENT: Other tests on the market tell you their findings but do not give your results, your Genotype, so you and your practitioner can further investigate.
While your DNA does not change, your lifestyle does, and our program is designed to accommodate a patient’s commitment level to healthier lifestyle habits.
Competition
THEIR TEST:
• Many other companies obtain the sample through saliva, which is less reliable than the cheek swab.
• Evaluate fewer SNPs (often 12–20) and health areas (1–2), requiring the purchase of several different panels to get the comprehensive analysis provided by Gene SNP
THEIR PLAN: Often offers a report with limited education about the health impact of the gene
THEIR SUPPLEMENTS: Most other genetic analyses do not offer supplements and often divert a patient to another health source for management.
THEIR COMMITMENT: Does not include a comprehensive genomic program that helps guide you and your practitioner with everyday steps toward a healthy lifestyle.
Obviously, genetics plays a crucial role in how our bodies grow and age, especially when it comes to our hormones, neurotransmitters and diet. In combination, they have an impact on our stress and sleep response. According to current research, nearly 70 percent of office visits today and a large percentage of prescriptions today are to help manage sleep and emotional liability. Some of these responses are a result of genetics. Variations in our genetic code can have both positive and negative effects on how our bodies manage stress and hormones. For example, one particular gene variation, BDNF, plays a role in comfort food eating and decreased learning, while another, HTR2311, codes for poor response to pharmaceutical intervention to support a healthy mental outlook.
Depression is a feature of some psychiatric syndromes such as major depressive disorder but it may also be a normal reaction to certain life events. A recent identification of obesity predisposing genes that are highly expressed in the brain raises the possibility of their genetic contribution to depression. Multiple variations contribute to polygenic obesity and may contribute to depression. Insomnia, excessive sleeping, fatigue, aches, pains, digestive problems or reduced energy may also be present. Most likely you don't know if you have these gene variations, which means you don't know what actions you can take to help maintain your optimal health.
What does Gene SNP test for related to mental and emotional health?
FAIM2 |
Some variants are protective in brain aging, responsive to mixed fatty acids for brain health |
SEC16B |
Required for protein transfer resulting in healthy energy metabolism within the mitochondria |
ETV5 |
This gene influences dopaminergic neurotransmission affecting startle response, attention and sleep |
MC4R313 |
This genes is associated with a capacity for efficient energy utilization and improved satiety signals |
BDNF |
This protein is found in regions of the brain that control eating, drinking and body weight |
TAS2R38-98 |
This gene controls the ability to taste glucosinolates, bitter-tasting compounds found in plants of the family Brassica. Some variants are accompanied by the desire to eat salt to mask bitter flavor |
MC4R |
This gene is associated with the appetite-stimulating effects of the enzyme AgRP, a neuropeptide of the brain |
TAS2R38-66 |
This gene controls feeding disinhibition, restraint and hunger |
HTR2A |
This gene is a subtype of the serotonin receptor A and affects neural activity, perception, cognition and mood and emotional control |
NEGR1 |
This gene is related to neurological activity in the hypothalamus |
LEP039 |
This gene regulates leptin which is secreted by white adipocytes for regulation of body weight |
DRD2277 |
This gene inhibits adenylyl cyclase activity and is involved in the regulation of appetite and growth hormone |
DRD2497 |
This gene controls the synthesesof dopamine in the brain |
COMT |
Breaks down catecholamines such as dopamine, epinephrine and norepinephrine, related to emotional patterns |
NBPF3 |
Neuroblastoma breakpoint family, member 3 associated with pyridoxine clearance |
FUT2 |
Responsible for B-12 metabolism and glutathione activity related to intrinsic factor and bacterial adhesion |
MTHFR |
Associated with Methylenetetrahydrofolate reductase deficiency |
The nutraMetrix®️ Gene SNP DNA Analysis tests for 17 genes and their variations associated with behavioral health. While no amount of food or exercise will physically alter our genes, with proper nutritional supplementation and lifestyle changes, you can maintain the functioning of your gene variations to maintain optimal health.
You do everything you can to maintain a healthy body weight. You exercise. You eat healthy foods. You might even take supplements. But sometimes it's not just what you do that makes a difference; it could be what you're made of—literally.
Genetics plays a crucial role in how efficiently we burn fat with exercise and how capable our bodies are to perform aerobic exercise. Variations in our genetic code can have both positive and negative effects on how our bodies react to the foods we eat and the workouts we put ourselves through. For example, one particular gene variation—FTO—could lead to increased fat accumulation in men and higher fat mass in women.
Most likely you don't know if you have these gene variations, which means you don't know what actions you can take to help maintain your optimal health. The Gene SNP DNA Analysis analyzes gene variants and your lifestyle choices to compile a personalized Weight and Wellness report that provides recommendations regarding lifestyle, diet, exercise and supplementation. The Gene SNP DNA Analysis can help your practitioner customize a program for you so you have a targeted plan instead of questioning how these gene variations affect the choices you make—from diet to exercise to supplementation—so you can maintain optimal health.
What does Gene SNP test for related to weight management?
FTO609 |
Functionally this gene demonstrates lower responsiveness to satiety signals and increased risk for obesity |
FTO812 |
Shown to contribute to early onset of obesity in both adolescents and adults |
FTO980 |
This gene functions to reverse damage to DNA & RNA by oxidative demethylation |
TAS1R3 |
Can cause an inability to taste sucrose along with the tendency to over-eat due to signaling response to feeding |
ADIPOQ56 |
Important positive adipokine involved in the control of fat metabolism and insulin sensitivity |
ADIPOQ539 |
This gene is an important adipokine involved in the control of fat metabolism and insulin sensitivity and is expressed exclusively in adipose tissue |
BDNF |
The BDNF protein is found in the regions of the brain that control eating, drinking and body weight |
PCSK1_2 |
This gene functions in the proteolytic activation of hormones and neuropeptide precursors |
FAIM2 |
This gene is associated with energy storage and increased risk of obesity, hyperlipidemia and endothelial dysfunction |
MC4R313 |
This protein is affected by sensitivity to the hormone leptin and limited by the hormone ghrelin |
DRD2 |
This gene is linked to how the brain processes reward signals |
SEC16B |
This gene is linked to hepatic lipase activity and risk of extreme obesity in childhood and obesity in adults for certain genotypes |
TMEM18 |
This gene has been identified as a strong indicator of the risk advanced glycation end-products, childhood obesity and obesity in adults |
NEGR1 |
Heavily involved with the risk for childhood obesity |
SH2B1 |
This gene influences cytokine and growth factor signaling as well as cellular transformation |
PPARD |
Promotes Beta Oxidation of fatty acids for energy |
PPARG |
Key regulator of adipogenesis, lipid and glucose homeostasis |
KCTD10 |
This gene plays a key role in the activity of this enzymes initiation of pre-adipocytes to become mature adipocytes |
KCTD15 |
This gene plays a role in inhibition of early adipogenesis |
LEP039 |
This gene regulates leptin, leptin is a protein secreted by white adipocytes for the regulation of body weight |
LEPR |
Direct correlation with resting metabolic rate |
INSIG2 |
The gene mediates feedback control of cholesterol sythesis by controlling HMG CoA Reductase |
The nutraMetrix®️ Gene SNP DNA Analysis tests for 22 genes and their variations associated with weight, hormones and energy. While no amount of food or exercise will physically alter our genes, with proper nutritional supplementation and lifestyle changes, you can optimize the functioning of your gene variations to maintain optimal health.
When it comes to heart health, there are a number of things you can do to promote your health. Reduce sugar, eat more fiber, exercise, and do it safely. Stop smoking. Relax. This is a lifestyle, however just as important are gene variations associated with heart health. Our genetic variations can have both positive and negative effects on our heart. The negative impact variation combined with an unhealthy diet or lifestyle may negatively influence overall health.
Most likely you don't know if you have these gene variations, which means you don't know what actions you can take to help maintain your optimal health. The nutraMetrix®️ Gene SNP DNA Analysis analyzes gene variants and your lifestyle choices to compile a customizable Weight and Wellness report. Your Health practitioner will then provide recommendations regarding lifestyle, diet, exercise and supplementation.
And unlike other tests on the market, the nutraMetrix®️ Gene SNP DNA Analysis offers a unique look at your heart health—not merely making recommendations on a single factor. The nutraMetrix®️ Gene SNP DNA Analysis can help you understand how these gene variations affect the choices you make - from diet to exercise to supplementation - so you can maintain optimal health.
What does Gene SNP test for related to heart health?
FAIM2 |
Involved in the programmed cell death induced by the fatty acid synthase (FAS) enzyme and various apoptotic stimuli |
SEC16B |
Required for protein transfer resulting in healthy energy metabolism within the mitochondria |
FTO609 |
This FTO enzyme has been associated with oxidative stress and demethylase activity and may be linked to cellular repair |
FTO812 |
Functions to reverse damage by oxidative demethylation that can lead to obesity and other hormonal metabolic concerns |
FTO980 |
This gene functions to reverse damage to DNA & RNA by oxidative demethylation |
INSIG2 |
Mediates feedback control of cholesterol synthesis by controlling HMG CoA Reductase. Insulin-induced receptor-2 is affected by adiponectin levels |
ETV5 |
Plays a role in regulating cellular systems associated with obesity, triglycerides, cell communication and immunity |
INTERGENIC |
An important enzyme in HDL metabolism |
ALDH2 |
Mitochondrial enzyme responsible for breaking down acetaldehyde produced by ethanol |
APOA2 |
Prolific protein of high density lipoprotein particles |
DHCR7 |
Catalyzes the conversion of 7-dehydrocholesterol to cholesterol using NADPH as a cofactor |
LIPC |
Dual functions of triglyceride ligand/bridging, ecodes hepatic triglyceride lipase |
ACTN3 |
Protein codes primarily in skeletal muscle and functions as a structural component of sacromere Z line |
SH2B1 |
Influences cytokine and growth factor receptor signaling as well as cellular transforamtion |
MMAB |
Defect in the synthesis of adenosylcobalamin |
PPARD52 |
Promotes beta oxidation of fatty acids for energy |
MTHFR |
Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methione |
PCSK1_2 |
Functions in the proteolytic activation of hormones and neuropeptide precursors; Insulin Insensitivity |
KCTD10 & 15 |
Inhibits pre-adipocytes to become mature adipocytes; key association with C/EBPa |
ADIPOQ56 & 39 |
Positive adipokine involved in the control of fat metabolism and insulin sensitivity; associated with adiponectin deficiency with mutations |
EDN1 |
A potent peptide hormone regulating cardiovascular, renal, pulmonary and neural tissue tone |
COMT |
Breaks down catecholamines. Elevated levels of catecholamines can lead to increased heart rate, agitation and impulsive behavior. |
SLC2A2 |
Elevated Sugar Intake; Elevated Serum Cholesterol |
FUT2 |
Responsible for B-12 metabolism and glutathione activity related to intrinsic factor and bacterial adhesion |
CYP2R1 |
Cytochrome P450 enzyme involved in nutrient metabolism and synthesis of cholesterol, steroids and other lipids |
The nutraMetrix®️ Gene SNP DNA Analysis tests for 27 genes and their variations that are associated with heart health. While no amount of food or exercise will physically alter our genes, with proper nutritional supplementation and lifestyle changes, you can maintain the functioning of your gene variations to maintain optimal health.
Blood sugar is vital to human function and must be consistently kept at a steady level to maintain good health. Blood sugar impacts numerous aspects of health, from cognitive function to energy to heart health, and more.
Blood sugar refers to glucose in the blood stream. In order for our cells to get the energy they need to maintain proper bodily functions, we must be able to efficiently move glucose in the blood into our cells. Because of the many critical functions that depend on it, blood sugar levels that are too low or too high are dealt with by the body in an urgent manner.
Some genetic variations are associated with the body's ability to efficiently clear glucose from the blood. A variant of the SLC2A2 gene may encourage a higher resting glucose level. Knowing this can help a person adjust their diet and exercise routines, which can help the body to utilize insulin more efficiently, or possibly receive a recommended nutraceutical to help maintain healthy insulin activity in the body.
Most likely you don't know if you have these gene variations, which means you don't know what actions you can take to help maintain your optimal health. The Gene SNP DNA Analysis analyzes gene variants and your lifestyle choices to compile a personalized weight and wellness report that provides recommendations regarding lifestyle, diet, exercise and supplementation. The Gene SNP DNA Analysis can help you understand how your genes affect the choices you make - from diet to exercise to supplementation - so you can maintain optimal health.
What does Gene SNP test for related to blood sugar?
MC4R |
Protein affected by sensitivity to the horomone Leptin and limited by the hormone Ghrelin |
TMEM18 |
This Gene is responsible for minimizing glycation and oxidative stress when carbohydrates, proteins and fats link. |
FTO609 |
This FTO enzyme has been associated with oxidative stress and demethylase activity and may be linked to cellular repair |
FTO812 |
This Gene functions to reverse damage by oxidative demethylation that may contribute to obesity or other concerns related to hormonal metabolic function. |
SH2B1 |
This Gene influences cytokine and growth factor receptor signaling as well as cellular transformation. Some alleles carry the risk of diminished activity in insulin receptors. |
LEP039 |
This Gene regulates leptin, leptin is a protein secreted by white adipocytes for regulation of body weight. |
PCSK1_2 |
This Gene functions in the proteolytic activation of horomones and neuropeptides precursors. |
ADIPOQ56 |
Important positive adipokine involved in the control of fat metabolism and insulin sensitivity. |
LEPR |
This SNP is a cytokine receptor fot the fat-cell specific hormone leptin. |
APOA2 |
This Gene greatly influences how your body processes fat. |
ADIPOQ539 |
This Gene is an important adipokine involved in the control of fat metabolism and insulin sensitivity. |
PPARG |
Key regulator of adipogenesis and glucose homeostasis. Receptor that binds peroxisome proliferators such as lipids and fatty acids. |
PPARD52 |
Master regulator of adipogenesis as well as a potent modulator of whole-body lipid metabolism and insulin sensitivity. |
FTO980 |
This Gene functions to reverse DNA and RNA damage by oxidative demethylation. It is alpha-ketoglutarate-dependent. |
SLC2A2 |
Major glucose transporter in the mammalian blood-brain barrier. |
CYP2R1 |
Cytochrome P450 enzyme. Involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. |
BCM01 |
Catalyzesthe oxidative cleavage of beta-carotene into two retinal molecules. |
GC |
Binds to vitamin D and its plasma metabolites. Responsible for transport to target tissues. |
BCM01-331 |
Catalyzesthe oxidative cleavage of beta-carotene into two retinal molecules. |
The nutraMetrix®️ Gene SNP DNA Analysis tests 19 genes and their variations associated with blood sugar. While no amount of food or exercise will physically alter our genes, with proper nutritional supplementation and lifestyle changes, you can maintain the functioning of your gene variations to maintain optimal health.
Nutrients, Detoxification & Immunity
With the falling levels of estrogen (in women) and testosterone (in men) as we age and its associated premature aging, you may have bone density below a normal level or poor detoxification pathways that may have an impact on hormones, metabolic function, and healthy aging.
Obviously, genetics plays a crucial role in how our bodies grow and age, especially when it comes to our metabolism. Variations in our genetic code can have both positive and negative effects on how our body utilizes nutrients. For example, one particular gene variation - GC - could lead to better bone formation and retention with exercise.
Most likely you don't know if you have these gene variations, which means you don't know what actions you can take to help maintain your optimal health. The Gene SNP DNA Analysis analyzes gene variants and your lifestyle choices to compile a personalized Health Action Plan that provides recommendations regarding lifestyle, diet, exercise, and supplementation. The Gene SNP DNA Analysis can help you understand how these gene variations affect the choices you make - from diet to exercise to supplementation - so you can maintain optimal health.
What does Gene SNP test for related to nutrient impact?
ALDH2 |
Mitochondria; Detoxification of Ethenol |
GC; CYP2R1; DHCR7 |
Vitamin D use; bone density; Cardiovascular Health |
TAS2R38 |
Poor SaitiSatietyals; Detoxification |
CYP1A2 |
Caffeine Metabolism; Cardiovascular Health |
NCR3 |
Poor immune Signals; Inflammatory Response |
Intergenic; BCM01; BCM0131 |
Carotenoid and Tocopherol Metabolism; Oxidation |
MCM6 |
Lactose Intolerance |
MMAB; FUT2; NBPF3 |
Defect in synthesis of B-12; B-6; Homocysteine |
The nutraMetrix®️ Gene SNP DNA Analysis tests for fourteen (14) genes and their variations associated with nutrient utilization. While no amount of food or exercise will physically alter our genes, with proper nutritional supplementation and lifestyle changes, you can maintain the functioning of your gene variations to maintain optimal health.